PRF EZ Gel in Newport Beach

Medically reviewed by Naomi Barrett, NP-C, certified nurse practitioner. Reviewed October 13, 2026.

Naomi Barrett, NP-C is a certified nurse practitioner specializing in dermatology, and the founder and lead injector at Injection Artistry in Newport Beach. She has trained other injectors in facial aesthetics since 2015. About Naomi

PRF EZ Gel is an injectable prepared from a small sample of your own blood. Platelet rich fibrin, the part of your blood that carries platelets and their growth factors, is combined with a soft gel made by warming and cooling your own plasma, and the mixture is placed where the face has lost support or where the skin has thinned. At Injection Artistry in Newport Beach, Naomi Barrett, NP-C draws, prepares and injects PRF EZ Gel and liquid PRF in one visit for patients from across Orange County, most often under the eyes, in the cheeks and temples, and along the smile lines.

PRF EZ Gel at a glance

What it is: an injectable made from your own blood. Platelet-rich fibrin (PRF) combined with a gel formed from your own plasma. No hyaluronic acid and no manufactured filler material.
Two forms: liquid PRF, which stays thin and is placed in the skin for texture and fine lines, and PRF EZ Gel, which holds its shape and is placed where volume has been lost.
Areas Naomi treats: under the eyes, cheeks and midface, temples, smile lines and marionette lines, and fine or crepey skin on the face. PRF is also used after microneedling and after an UltraClear laser session.
Appointment: blood draw, preparation and injection in one visit. Plan on about an hour.
Sessions: planned as a series, usually spaced four to six weeks apart, with one or two maintenance visits a year if you choose to keep the result up.
Who injects: Naomi Barrett, NP-C, certified nurse practitioner and lead injector.
Where: Injection Artistry, 20301 SW Birch St, Suite 203, Newport Beach, CA 92660. Call or text (949) 531-1939.

What PRF EZ Gel is

Platelet-rich fibrin is a concentrate of your own platelets held in a fibrin mesh. A small amount of blood is drawn from your arm and spun in a centrifuge, which separates the blood into layers, and the layer rich in platelets and fibrin is collected. PRF is prepared without additives, and the fibrin holds the platelets so that their growth factors are released gradually rather than all at once.

EZ Gel adds a second step. Part of the plasma from the same draw is warmed and then cooled, which turns it into a soft gel, and that gel is combined with the PRF. The result is thicker than liquid PRF, so it can be placed where the face needs support, not only in the skin. Everything in the syringe came from your own blood.

Liquid PRF or PRF EZ Gel

Liquid PRF stays thin and is injected in or just under the skin, where the aim is skin quality: fine lines, crepey texture, and the thin skin under the eyes. PRF EZ Gel holds its shape, so Naomi uses it where there is a hollow to support, such as the tear trough, the temple or the cheek. Many plans use both in one visit, and the choice is made at your consultation from what your face needs.

How it differs from a hyaluronic acid filler

A hyaluronic acid filler adds volume the moment it is placed. PRF EZ Gel is placed to give support on the day, and any further change builds over weeks as the body responds, so the result is gradual rather than immediate. PRF EZ Gel contains no hyaluronic acid, which means the enzyme used to dissolve an HA filler does not apply to it. If you are weighing the two, our comparison of PRF EZ Gel and traditional fillers walks through the differences, and the dermal fillers page covers the hyaluronic acid products we carry.

Where Naomi uses PRF EZ Gel

Naomi plans PRF EZ Gel around the areas where the skin is thin or where volume has started to go. On the face that most often means:

Under the eyes, where a hollow between the lower lid and the cheek reads as shadow or tiredness. This area has its own section below.
The cheeks and midface, where early volume loss flattens the contour.
The temples, where hollowing shows as a dip beside the brow.
Smile lines and marionette lines, the folds that run from the nose to the mouth and from the mouth toward the chin.
Fine lines and crepey skin, with liquid PRF placed in the skin itself.

She also applies or injects PRF after microneedling and after an UltraClear laser session, and some patients pair PRF EZ Gel with a hyaluronic acid filler in a layered plan. In every area the aim is support and skin quality, not a fixed amount of volume, and whether a combination fits you is decided at your consultation.

PRF EZ Gel under the eyes

The under-eye area is the most common reason patients ask Naomi about PRF EZ Gel. The skin here is the thinnest on the face, and a hollow between the lower lid and the cheek, the tear trough, casts a shadow that can read as dark circles or a tired look even after a full night’s sleep. Some patients prefer not to place a hyaluronic acid filler in this area, and PRF EZ Gel, made from their own blood, is what they ask for instead. At your consultation, Naomi looks at whether what you see is shadow from a hollow or color in the skin itself, because the plan is different for each.

The research on platelet treatments around the eyes is encouraging and still limited. A 2025 systematic review of 14 studies found that PRF was associated with improvements in skin texture, wrinkles, and crepiness around the eyes, while PRP showed stronger evidence for pigmentation; the authors concluded that the evidence does not show one is better than the other and that larger controlled trials with standardized measures are needed. A 2021 meta-analysis of PRP for the area around the eyes, covering 19 studies and 455 patients who had on average three treatments, found higher satisfaction than controls in the three randomized trials it could pool and called for longer follow-up.

In practice, Naomi describes the under-eye result as a gradual change in skin quality and a softening of the hollow, planned over a series, rather than the immediate fill a hyaluronic acid product gives. Bruising and swelling show more readily under the eyes than elsewhere on the face, so plan a first session for a week without photographs or events.

What happens at your appointment

Consultation and plan. Naomi reviews your health history, the medications and supplements you take and what you want to change, then decides with you whether liquid PRF, PRF EZ Gel or both fit, and where.
Blood draw. A small amount of blood is drawn from your arm, as it would be for a routine blood test.
Preparation. The tubes are spun in a centrifuge. For EZ Gel, part of your plasma is warmed and cooled into a gel and combined with the PRF. Only your own blood is used, and it is prepared and injected in the same visit.
Numbing. A topical numbing cream can be applied before injection. Most patients describe mild discomfort rather than pain.
Injection. Naomi places the PRF or the gel in the planned areas. From draw to finish, plan on about an hour.
Afterward. You can go back to your day. Expect some swelling, redness, and possibly bruising at the injection sites for a few days. Naomi gives you aftercare instructions for the areas treated before you leave.

Results: what to expect and when

PRF EZ Gel results arrive slowly. Gel placed on the day gives support on the day; the rest of the change, if it comes, builds over the following weeks. The American Academy of Dermatology says of platelet treatments for the skin that if you get results, the full effects appear within a few weeks to months, and that most patients who get results have three or more treatments. That matches how Naomi plans it: a series of sessions spaced four to six weeks apart, then, if you want to keep the result up, one or two maintenance visits a year.

How long a result lasts varies from person to person and by area, and we do not quote a figure for it. A 2018 review published in Plastic and Reconstructive Surgery looked at 22 studies of PRP for facial cosmetic use and found promising results and a low complication rate, alongside real limits in the evidence: preparation methods varied, few studies had control groups, and follow-up was too short to say how long the benefits last. Naomi reviews the treated areas with you at each follow-up so you can judge the change against your own face.

Risks, side effects and aftercare

Most people have some pain, bruising and swelling at the injection sites, and these tend to go away within a few days. Under the eyes, bruising and swelling tend to show more and take a little longer to settle.

The main risk with any platelet treatment is in how the blood is handled. Your blood has to stay sterile from the draw to the injection, and the only blood that can go back into you is your own. At Injection Artistry the draw, the preparation and the injection happen in the office in the same visit, with nothing added from outside your body.

Because PRF EZ Gel is injected into the face, it carries the same risk as any facial injection: material entering a blood vessel. The chance is small, but the consequences can be serious and lasting, including changes to vision, damage to the skin and stroke. The areas around the eyes and the nose carry more of this risk than the rest of the face, and Naomi plans treatment in those areas conservatively.

Call the clinic right away at (949) 531-1939, or seek emergency care, if after treatment you notice any change in your vision; signs of a stroke, including sudden difficulty speaking, numbness or weakness in the face, arms or legs, face drooping, severe headache, dizziness or confusion; skin near an injection site turning white, gray or blue; unusual pain during or shortly after treatment; or increasing redness, warmth, swelling or discharge at a draw or injection site, which can be signs of infection.

PRF EZ Gel is not for everyone. At your consultation Naomi reviews your health history, the medications and supplements you take, and the condition of the skin where treatment is planned, and she will tell you if she recommends against it or would rather wait. Aftercare is specific to the areas treated, and Naomi goes through it with you before you leave.

Cost and financing

PRF EZ Gel is priced by the plan: which areas, whether liquid PRF, PRF EZ Gel, or both, and how many sessions. Naomi quotes the price at your consultation and tells you what it includes. Financing through Cherry is available, and our new patient specials page lists current offers.

Who performs PRF EZ Gel at Injection Artistry

Naomi Barrett, NP-C performs PRF EZ Gel at Injection Artistry. She is a certified nurse practitioner specializing in dermatology, the founder and lead injector at the clinic, and she has trained other injectors in facial aesthetics since 2015. Steve Yoelin, MD, an ophthalmologist, is the practice’s medical director.

Frequently asked questions

Is PRF EZ Gel a filler?

PRF EZ Gel is used the way a filler is used, placed where the face needs support, but it is made from your own blood rather than hyaluronic acid or any manufactured material. It gives some support on the day, any further change builds over weeks, and it cannot be dissolved with the enzyme used on hyaluronic acid fillers.

What is the difference between PRF and PRP?

Both are concentrates of your own platelets. Platelet rich plasma (PRP) is prepared with an additive and stays liquid; platelet rich fibrin (PRF) is prepared with none, so it forms a fibrin mesh that releases its growth factors more slowly. At Injection Artistry we use PRF, as liquid PRF or as PRF EZ Gel.

How many sessions will I need?

Most plans are a series of sessions spaced four to six weeks apart, then one or two maintenance visits a year if you want to keep the result up. Naomi sets the number at your consultation and adjusts it at follow-up.

Does PRF EZ Gel hurt?

A blood draw and a series of small injections are involved. A topical numbing cream can be applied first, and most patients describe mild discomfort rather than pain.

How much downtime is there?

Plan for a few days of swelling, redness and possible bruising at the injection sites; most people go back to their day the same day. Under the eyes, bruising shows more.

Can PRF EZ Gel be combined with microneedling or laser?

Yes. Naomi applies or injects PRF after microneedling and after an UltraClear laser session for some patients, and some patients combine PRF EZ Gel with a hyaluronic acid filler in a layered plan. Whether a combination suits you is decided at your consultation.

Book a PRF EZ Gel consultation

A consultation is the first step. Naomi looks at the areas you want to change, tells you whether liquid PRF, PRF EZ Gel or another treatment fits, and quotes the plan. Call or text (949) 531-1939, or send us a message. Injection Artistry is at 20301 SW Birch St, Suite 203, Newport Beach, CA 92660.

Keep reading

Biostimulators at Injection Artistry: Sculptra, Radiesse and PRF EZ Gel, as we group them.
PRF EZ Gel vs. traditional fillers: how the two compare, point by point.
Sculptra in Newport Beach and Radiesse: the two other treatments on our biostimulators menu.
Microneedling with PRF: PRF applied during a microneedling session.
Hair restoration with PRF: PRF used on the scalp.
Injectables in Newport Beach: every injectable we offer, in one place.

Sources

American Academy of Dermatology. Is platelet-rich plasma the secret to younger-looking skin?. https://www.aad.org/public/cosmetic/younger-looking/platelet-rich-plasma-secret-to-younger-skin. Accessed 10/06/2026 (page undated).
American Society of Plastic Surgeons. Platelet-Rich Plasma for Cosmetic Facial Procedures: Promising Results, but Evidence Has Limitations (press release on a review in Plastic and Reconstructive Surgery, May 2018). https://www.plasticsurgery.org/news/press-releases/platelet-rich-plasma-for-cosmetic-facial-procedures-promising-results-but-evidence-has-limitations. 04/27/2018.
American Society of Plastic Surgeons. Platelet-Rich Fibrin May Lead to Better Outcomes with Fat Grafting (press release on a study in Plastic and Reconstructive Surgery). https://www.plasticsurgery.org/news/press-releases/platelet-rich-fibrin-may-lead-to-better-outcomes-with-fat-grafting. 05/30/2019.
Sollitto CF, Narduzzi M, Wolinsky C. A Systematic Review of Platelet-Rich Plasma Versus Platelet-Rich Fibrin for Periorbital Rejuvenation. Journal of Cosmetic Dermatology. 2025;24(11):e70524. https://pubmed.ncbi.nlm.nih.gov/41190633/. doi 10.1111/jocd.70524.
Evans AG, Ivanic MG, Botros MA, et al. Rejuvenating the periorbital area using platelet-rich plasma: a systematic review and meta-analysis. Archives of Dermatological Research. 2021;313:711-727. https://link.springer.com/article/10.1007/s00403-020-02173-z. doi 10.1007/s00403-020-02173-z.